Dr. Isaac Perle
General, Cosmetic and Emergency Dentist
Dr. Perle received his dental degree from the University of Pennsylvania in 1979. He has run his own dental practice in Brookline, Massachusetts, since 1980.
- Massachusetts Dental Association
- Currently clinical assistant professor University of Penn school of Dental Medicine
- Alpha Omega International Dental Fraternity
- Served on the faculty of both the Harvard School of Dental Medicine and the Forsyth Dental Center
- Previously served as mentor for Boston University’s APEX program.
- President and Founder of the Jerusalem Dental Center for Children, the largest non-profit children’s dental clinic in Jerusalem.
- Was nominated as Top Dentist from 2017-2020
In keeping with his own philosophy of “patients first”, he is known for being very gentle, taking time to talk to his patients to make sure that they are, above all, comfortable and at ease with the procedures.
Working to his own high standards, he accepts nothing but the best for his patients, from himself and from his staff.

“1000” Plaque presented to Dr. Isaac Perle by Invisalign Vice President for Completing 1000 Cases